IBD in dogs
IBD – Inflammatory bowel disease in dogs
IBD is inflammatory bowel disease in dogs. The exact incidence is not known. It is defined as a spectrum of gastrointestinal
(ie the gastrointestinal tract of respective)
diseases with chronic inflammation of the stomach, small intestine and / or colon of unknown cause.
The diagnosis is an exclusion diagnosis; other, explaining the symptoms causes must be ruled out.
The diagnosis is usually made ??with ongoing gastrointestinal symptoms such as nausea, vomiting, diarrhea, weight loss, vomiting blood or
bloody/mucoid defecation, do not respond by conventional treatments for parasites on antibiotics or other common gastrointestinal therapies.
Moreover, in further investigations must (faeces for parasites, bacteria, and especially Giardia, blood tests including CRP, folate, vitamin B12,
thyroid, pancreas and liver function tests, kidney function, ultrasound, x-ray, etc.) any other causes are excluded.
A sampling in an endoscopic examination (gastric and / or colonoscopy) secures with typical histological picture is usually the diagnosis.
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The reason of the disease remains unclear. The currently most common theory is the hypersensitivity reaction theory. Here, it is thought that the
lining of the gastrointestinal tract loses its natural tolerance to bacteria and food and this leads to an excessive inflammatory and immune response.
This means that e.g. certain food or normal intestinal bacteria are recognized as "foreign" and "dangerous"
and the immune system tries by inflammation, fight off these "intruders". Thus was a excessive immune forming cause of the disease.
Another theory is an overgrowth of the small intestine by bacteria. In addition, genetic factors are suspected, because some forms of IBD show
a breed predisposition (Boxer, German Shepherd, SharPei, Basenji) (Rotter 2005). Probably the action of different factors is that lead to the triggering
of the disease.
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The disease is considered to be chronic and often runs lightening.
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Most affected animals require lifelong therapy.
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literature:
Zentek J; Hellweg P; Khol-Parisini A; Weingart C; Kohn B; Münster M, Kleintierpraxis, 52 (6), 2007, 356 – 367
http://geb.uni-giessen.de/geb/volltexte/2006/2693/pdf/RotterSilke-2005-12-02.pdf
Jergens AE, et al (2003): A scoring index for disease activity in canine inflammatory bowel disease. In: J Vet Intern Med. 2003 May-Jun;17(3):291-7.
2005 Report From: WSAVA Gastrointestinal Standardization Group (http://www.wsava.org/GIStandards1.htm)
state of research 07/2010
shortened, Copyright: Vera Engelbertz
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The full article can be read here: Article of Mrs. Engelbertz
I hope my translation is easy to understand.